collagen type X Advanced purifications Technologies

collagen type X Advanced purifications Technologies by Green Chemistry ?

Microcore has more than two decades of experiences in research, manufacturing and scale up of many Nutrabioceuticals and Theraputicals. Our new innovations helps us to develope unique and GRAS Green enzyme technologies for the purification of Collagen type X from Egg Shell Membrane. Microcore Collagen Type V is derived from Egg Membrane Collagen Type X is a specialized, non-fibrillar collagen naturally present in the eggshell membrane (ESM). It plays a crucial role in bone and cartilage formation, particularly in the later stages of cartilage maturation.

 

  • Marker of cartilage maturation
    Type X collagen is produced by hypertrophic chondrocytes, indicating advanced stages of cartilage development.

  • Supports bone mineralization
    It contributes to endochondral ossification, the process by which soft cartilage gradually becomes hard, mineralized bone.

  • Helps joint integrity
    By supporting matrix organization, Collagen X contributes to healthy joint structure, especially in weight-bearing joints.

  • Natural anti-inflammatory and regenerative potential
    Egg membrane derived Type X is associated with natural bioactive peptides and growth factors that aid joint repair and reduce inflammation.



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    • Where it is used ?

    • Chondrocyte Activation
      Enhances the function of hypertrophic chondrocytes, enabling proper cartilage maturation.

    • Matrix Mineralization
      Facilitates deposition of calcium and phosphate, essential for bone strengthening.

    • Structural Support
      Works in synergy with collagen Types I, V, and other egg membrane proteins to reinforce cartilage and subchondral bone.

    • Inflammation Modulation
      Bioactive components of egg membrane help reduce inflammatory mediators (e.g., IL-1β, TNF-α), supporting joint comfort.

    • What are the advantages of collagen type X  ?

    • Essential for Collagen Fibril Formation
      Type V collagen regulates the assembly and diameter of collagen fibrils, ensuring proper structural organization of connective tissues.

    • Supports Hair Follicle Architecture
      It plays a key role in maintaining the extracellular matrix of the hair follicle, supporting root strength, follicle stability, and healthy hair growth.

    • Enhances Skin and Tissue Integrity
      By interacting synergistically with Types I and III collagen, it contributes to improved skin firmness, elasticity, and recovery from micro-damage.

    • Promotes Regenerative Processes
      Egg membrane naturally contains bioactive peptides and proteins that, along with Type V collagen, support tissue repair and remodeling.

    • Improves Scalp and Hair Health
      Its structural and hydrating properties help strengthen the hair shaft, reduce breakage, and support a healthier scalp environment.

    • Natural and Biocompatible Source
      Egg membrane provides a gentle, minimally processed, and well-tolerated form of Type V collagen suitable for nutraceutical and dermaceutical applications.

    • How  the  Specific Mechanisam of action works  ?

      Mechanism of Action of Collagen Type X (Egg Membrane Derived) ?.
       

    • Chondrocyte Activation
      Enhances the function of hypertrophic chondrocytes, enabling proper cartilage maturation.

    • Matrix Mineralization
      Facilitates deposition of calcium and phosphate, essential for bone strengthening.

    • Structural Support
      Works in synergy with collagen Types I, V, and other egg membrane proteins to reinforce cartilage and subchondral bone.

    • Inflammation Modulation
      Bioactive components of egg membrane help reduce inflammatory mediators (e.g., IL-1β, TNF-α), supporting joint comfort.


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    • When the Specific collagen type X molecule will be launched by Microcore ?


      The developments are at lab scale and expected to complete clinical studies and further launch  by 2028


       

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